Hexamethyldisilazane Manufacturers (HMDS)

HMDS, or Hexamethyldisilazane, is a versatile compound derived from organosilicon compound. It has a wide range of applications which makes it a valuable base precursor and reagent.

HMDS is primarily used in the pharmaceutical manufacturing for silylating processes, which is used in the production of antibiotics such as Cefprozil, Cefadroxil, along with antiretroviral drugs like Sofosbuvir, Lamivudine, and Emtricitabine. In addition, it also finds utility in the semiconductor industry that aids in enhancing the tearing strength of vinyl silicone rubber.

  • Cas Number 999-97-3

Title Specification
Appearance A Clear Colorless Liquid.
Solubility Insoluble in water & miscible in Acetone
Identification RT of the major peak in the chromatogram of the sample solution should correspond to that of the standard solution as obtained in chromatographic purity (By GC).
Specific gravity(@ 25oC) NMT 0.78 gml
Boiling Range 123 oC to 127 oC
HMDO (by GC) NMT 0.50 %
Chromatography purity (By GC.) NLT 99.00 %